Whole Genome Sequencing for Forensic Laboratories Workshop

Whole Genome Sequencing for Forensic Laboratories Workshop

Description:

In August 2023, the Center for Human Identification (CHI) at the University of North Texas Health Science Center became the first publicly accredited laboratory to implement SNP testing using MPS technologies for Forensic Genetic Genealogy (FGG). Since that time, the CHI has implemented a number of workflows for FGG cases, with the latest being whole genome sequencing (WGS).

This workshop will focus solely on WGS. The benefits of WGS will be discussed along with additional informatic and sequencing platform considerations. Molecular and bioinformatic workflows will be outlined and data from the CHI’s developmental validation will be shared.

 

Learning Outcomes:

  • Molecular workflow for whole genome sequencing
  • Bioinformatic needs for whole genome sequencing including an end-to-end open-source pipeline
  • Considerations for validation of a whole genome sequencing workflow
  • Details on performance from multiple platforms, including the generation of whole genome data on less expensive platforms such as the MiSeq

 

Intended Audience:

This workshop is intended for DNA analysts, technical leaders, supervisors, attorneys, genealogists, investigators, and judges, as well as for anyone wishing to bring whole genome sequencing online or for those considering sending their samples to an outside laboratory for whole genome sequencing. Some topic knowledge required.

Description:

In August 2023, the Center for Human Identification (CHI) at the University of North Texas Health Science Center became the first publicly accredited laboratory to implement SNP testing using MPS technologies for Forensic Genetic Genealogy (FGG). Since that time, the CHI has implemented a number of workflows for FGG cases, with the latest being whole genome sequencing (WGS).

This workshop will focus solely on WGS. The benefits of WGS will be discussed along with additional informatic and sequencing platform considerations. Molecular and bioinformatic workflows will be outlined and data from the CHI’s developmental validation will be shared.

 

Learning Outcomes:

  • Molecular workflow for whole genome sequencing
  • Bioinformatic needs for whole genome sequencing including an end-to-end open-source pipeline
  • Considerations for validation of a whole genome sequencing workflow
  • Details on performance from multiple platforms, including the generation of whole genome data on less expensive platforms such as the MiSeq

 

Intended Audience:

This workshop is intended for DNA analysts, technical leaders, supervisors, attorneys, genealogists, investigators, and judges, as well as for anyone wishing to bring whole genome sequencing online or for those considering sending their samples to an outside laboratory for whole genome sequencing. Some topic knowledge required.

Pricing:


  • Standard Registration$425
  • Student Registration$300

Fees include printed workshop materials, breakfast, lunch, and breaks

Workshop currently at capacity. A waitlist is available to join on our registration page.

Brought to you by

Worldwide Association of Women Forensic Experts

Co-Chair

Jennifer Cihlar

Assistant Professor, Microbiology, Immunology, and Genetics Department at UNTHSC

Dr. Jennifer Cihlar is an Assistant Professor in the Microbiology, Immunology, and Genetics Department at UNTHSC and a member of the UNTHSC Center for Human Identification’s Research Unit where her efforts focus on improving the forensic community’s ability to identity humans associated with crime, missing persons, and human and wildlife trafficking victims through forensic genomic research.

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Co-Chair

August Woerner

Assistant Professor, Microbiology, Immunology and Genetics, University of North Texas Health Science Center

August Woerner is an Assistant Professor in the department of Microbiology, Immunology and Genetics at the University of North Texas Health Science Center. Much of August’s current research focuses on whole genome sequencing, particular, its application to forensic genetic genealogy.

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Michael Coble

Executive Director, Center for Human Identification, UNTHSC

Michael Coble, PhD, is an Associate Professor and the Executive Director of the Center for Human Identification at the University of North Texas Health Science Center in Fort Worth, Texas. He is a Fellow of the American Academy of Forensic Sciences and a member of the International Society for Forensic Genetics. He serves as a commissioner of the Texas Forensic Science Commission and is an invited guest at the Scientific Working Group on DNA Analysis Methods (SWGDAM).

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Nicole Novroski

Associate Director, Center for Human Identification

Dr. Nicole Novroski is the Associate Director of the Center for Human Identification and holds an Associate Professor position within the College of Biomedical and Translational Sciences at UNTHSC.  Her current focus is the exploration of previously uncharacterized genetic markers for improved DNA mixture deconvolution and in the optimization of genetic workflows for forensic genetic genealogy.  

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