Supporting Your Laboratory During Probabilistic Genotyping Implementation: from Validation to Admissibility

Home » Supporting Your Laboratory During Probabilistic Genotyping Implementation: from Validation to Admissibility

Workshop

September 23, 2024 //
8:30 am -
5:00 pm //
Grand Oaks Ballroom PQ

Description:

Forensic laboratories are increasingly adopting probabilistic genotyping methods for the interpretation of DNA mixtures. Guidance for the validation and implementation of PG methods is evolving, with new documents being released after laboratories have implemented software. These include guidance from OSAC, ISFG, ENFSI, and NIST.

This workshop will cover the key recommendations for internal validation. We will discuss experimental design to meet the recommendations, summarize published material addressing these key issues, and discuss common challenges to the use of PG methods. Using interactive engagement, we will provide the audience with strategies to address new guidelines and to prepare for admissibility hearings for PG software.

Learning Outcomes:

To understand the relevant standards and recommendations for validation
Gain an appreciation of what data is publicly available to support Probabilistic Genotyping
Support your laboratory to effectively address common challenges to the use of Probabilistic Genotyping (e.g. relatives, “factor space”, source code availability, activity level propositions)

Intended Audience:

This workshop is intended for DNA analysts, supervisors, technical leaders, attorneys and judges. Some knowledge required.

Description:

Forensic laboratories are increasingly adopting probabilistic genotyping methods for the interpretation of DNA mixtures. Guidance for the validation and implementation of PG methods is evolving, with new documents being released after laboratories have implemented software. These include guidance from OSAC, ISFG, ENFSI, and NIST.

This workshop will cover the key recommendations for internal validation. We will discuss experimental design to meet the recommendations, summarize published material addressing these key issues, and discuss common challenges to the use of PG methods. Using interactive engagement, we will provide the audience with strategies to address new guidelines and to prepare for admissibility hearings for PG software.

Learning Outcomes:

To understand the relevant standards and recommendations for validation
Gain an appreciation of what data is publicly available to support Probabilistic Genotyping
Support your laboratory to effectively address common challenges to the use of Probabilistic Genotyping (e.g. relatives, “factor space”, source code availability, activity level propositions)

Intended Audience:

This workshop is intended for DNA analysts, supervisors, technical leaders, attorneys and judges. Some knowledge required.

Pricing:

Standard Registration$345
Student Registration$195

Fee includes breakfast, lunch, breaks and handouts

Workshop currently at capacity. A waitlist is available to join on our registration page.

Agenda:

8:30 – 8:40AM

Welcome and Introduction – Michael Coble

8:40 – 9:40AM

Relevant Standards – Michael Coble

9:40 – 10:45AM

Publicly Available Data – Jo Bright

10:45 – 11:00AM

BREAK

11:00AM – 12:20PM

Issues for Admissibility I – Richard Wivell

12:20-1:30PM

LUNCH

1:30 – 2:45PM

Experimental Design – Michael Coble

2:45 – 3:00PM

Issues for Admissibility II – Jo Bright

3:00 – 3:15PM

Exercise – Richard Wivell

4:30 – 5:00PM

Questions

Chair

Michael Coble

Executive Director, Center for Human Identification, UNTHSC

Michael Coble, PhD, is an Associate Professor and the Executive Director of the Center for Human Identification at the University of North Texas Health Science Center in Fort Worth, Texas. He is a Fellow of the American Academy of Forensic Sciences and a member of the International Society for Forensic Genetics. He serves as a commissioner of the Texas Forensic Science Commission and is an invited guest at the Scientific Working Group on DNA Analysis Methods (SWGDAM).

Jo-Anne Bright

Environmental Science and Research Limited (ESR) New Zealand

Jo-Anne Bright is a Senior Science Leader within the Forensic Biology group at the Institute of Environmental Science and Research Limited (ESR) New Zealand, where she has worked since 1999. Jo is one of the co developers of STRmix™, expert software for the interpretation of forensic DNA profiles and the new Australasian standard.

Richard Wivell

Senior Scientist, Institute of Environmental Science and Research Limited

Richard Wivell is a Senior Scientist within the STRmixTM team at the Institute of Environmental Science and Research Limited, New Zealand where he has worked since 2008. Before moving to New Zealand, Richard was a Forensic Scientist for the Metropolitan Police Service and the Forensic Science Service in the UK.

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