Forensic Science Validation Workshop

Validation is a critical part of the scientific process for assessing whether a technique is technically sound and can be used in laboratories to produce robust and defensible analytical results. In the forensic science context, validation is mandated for laboratories accredited under the ISO/IEC 17025 standard, yet the standard tells laboratories that methods must be validated but does not provide a rigorous framework describing how a method or technique can or should be validated. There is a critical need in the forensic science community for a scientifically based framework for how laboratories should approach validation. Not only would this serve as a means for strengthening the robustness of validation studies designed to support the use of forensic science methods implemented in operational practice, but it would also serve to promote greater consistency in how validation is approached across different laboratories and disciplines throughout forensic science community. In support of this effort, RTI is working with NIST to provide a generalized framework that is applicable across multiple laboratories and disciplines to guide how laboratories should perform a scientifically defensible validation study.

This workshop will discuss and use validation data from rapid DNA systems as the focus of discussion. Important principles and new tools under development at NIST will be reviewed and demonstrated.

Tentative Agenda:

• Module 1: Opening and Introductions
  • Introduce the topic of validation, an overview of previous activities, and our purpose with this workshop (John Butler, NIST)
  • Review challenges regarding validation expressed by members of the community (Melissa Taylor, NIST)
• Module 2: Principles and Data Sharing Options
  • Share some key NIST validation principles and potential NIST data portal for sharing validation data (Henry Swofford, NIST)
• Module 3: Preparation and Implementation Strategies
  • Review some validation templates and grant funding options for rapid DNA (Jason Chute, RTI)
• Module 4: Demonstration of New Tool for Validation Data Assessment
  • Demonstrate a custom tool developed at NIST for evaluating rapid DNA validation data and train analysts on its use (Steve Lund, NIST)
• Module 5: Wrap-up and Path Forward
  • Discuss a path forward using a community-based validation approach with a Research Grade Test Material (RGTM) and other tools available (Erica Romsos, NIST)