We all know that it is very difficult to, not only develop a new forensic genetic method, but also apply it successfully to casework and get it accepted in court. With my laboratory I have worked since 2008 on the development of an massively parallel sequencing (MPS) based method to genotype short tandem repeat (STR) loci. After a lot of failures, we could finally receive ISO-17025 in 2015, for a complete pipeline that combines wet-work and bioinformatics and enables the reliable and reproducible sequencing of a set of autosomal STR loci and Y-STR loci. All this work culminated in January 2019 in, the conviction of a suspect of rape by the appeal court in Amsterdam, The Netherlands. As far as I am aware of, this was the first MPS-based conviction worldwide. This case, and a number of other case examples, will be discussed in my presentation.
We all know that it is very difficult to, not only develop a new forensic genetic method, but also apply it successfully to casework and get it accepted in court. With my laboratory I have worked since 2008 on the development of an massively parallel sequencing (MPS) based method to genotype short tandem repeat (STR) loci. After a lot of failures, we could finally receive ISO-17025 in 2015, for a complete pipeline that combines wet-work and bioinformatics and enables the reliable and reproducible sequencing of a set of autosomal STR loci and Y-STR loci. All this work culminated in January 2019 in, the conviction of a suspect of rape by the appeal court in Amsterdam, The Netherlands. As far as I am aware of, this was the first MPS-based conviction worldwide. This case, and a number of other case examples, will be discussed in my presentation.
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