Using public DNA databases, such as GEDmatch has led to closing over 50 cold cases since April of 2018, but few regulations have been put in place, and questions regarding privacy remain. Which types of cases warrant the use of investigative genealogy techniques and what/if any safeguards should be enacted? Craig Klugman, a Bioethicist at DePaul University details the issues surrounding commercial DNA databases, using these databases for investigative genealogy purposes, and offers some paths forward.