Demonstration of a Mitochondrial DNA-Compatible Workflow for Genetically Variant Peptide Identification from Human Hair Samples
Hair is an evidentiary sample that typically does not provide sufficient nuclear DNA for forensic analysis. Therefore, state-of-the-art forensic examination for hair samples include subjective microscopic evaluation, mitochondrial DNA (mtDNA) analysis, and more recently, proteomic genotyping (hair is composed of up to 95% protein by mass) that uses protein variation in the form of genetically […]
